Bojiong (Shanghai) Precision Machinery Technology Co., Ltd
Bojiong (Shanghai) Precision Machinery Technology Co., Ltd
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Biological Cell Four-wave Interferometric Sensor
  • Biological Cell Four-wave Interferometric SensorBiological Cell Four-wave Interferometric Sensor

Biological Cell Four-wave Interferometric Sensor

Our Biological Cell Four-wave Interferometric Sensor harnesses the powerful capabilities of four-wave interference to provide high-resolution imaging and analysis, enabling researchers and medical professionals to gain an unprecedented level of insight into cell morphology, dynamics, and interactions. This cutting-edge technology is expected to revolutionize the way we study and understand biological cells, offering new possibilities for the advancement of life sciences. BOJIONG Optoelectronics is eager to collaborate with researchers, academic institutions, and healthcare professionals worldwide to explore the full potential of our Biological Cell Four-wave Interferometric Sensor. Together, we can open up new frontiers in biological research and contribute to the progress of medical science.


The plug-and-play Biological Cell Four-wave Interferometric Sensor supports near-infrared and LED white light spectrum illumination. The imaging process does not require labeling or staining, and is capable of achieving in vivo 3D imaging at a rate of up to 24 frames per second. It can quickly be used in conjunction with any optical microscope to provide real-time measurements of the 3D phase distribution of the measured cells. It is capable of assessing cell volume and weighing. This sensor from BOJIONG is an ideal tool for label-free 3D live cell detection, biological tissue detection, germ cell detection, and micro/nano structure detection.

 

Item Specification

 

Light source type

LED, halogen lamp, and other broadband light sources

Wavelength range

400nm~1100nm  (for white light)

Target size

7.07mm × 7.07mm

Spatial resolution

13.8μ m

Phase output resolution

512×512

Absolute accuracy

10nmRMS

Phase resolution

≤ 2nmRMS

Dynamic range

≥130μ m

Sampling rate

24fps

Real-time processing speed

10Hz ( At full resolution )

Interface type

GIGE

Dimension

56.5mm × 43mm × 41.5mm

Weight

about 120g

Refrigeration method

none

  

Feature Of BOJIONG Biological Cell Four-wave Interferometric Sensor

 

 

 

◆Label-free 3D live cell imaging

◆Single-channel light self-interference, no reference light required

◆Compact size, plug and play

◆Suitable for all optical microscope upgrades and extensions

◆Broad spectrum 400nm~1100nm band

◆Extremely strong anti-vibration performance, no need for optical vibration isolation

◆Supports LED white light and short-wave infrared light source

 

 Application Of BOJIONG Biological Cell Four-wave Interferometric Sensor

 

This BOJIONG Biological Cell Four-wave Interferometric Sensor used in labeling free 3D living cell detection, biological tissue detection, germ cell detection, micro and nano structure detection.

 

Unmarked 3D live cell detection optical path detection optical path

3D Living cell microscope - Sample measurement of roundworm eggs

Sample measurement of ovarian granulosa cell tumor

Sample measurement through micro - nano structure


BOJIONG Biological Cell Four-wave Interferometric Sensor Details

 

BOJIONG Biological Cell Four-wave Interferometric Sensor  developed by a team of professors from Zhejiang University and Nanyang Technological University of Singapore, utilizes domestic patented technology and combines diffraction and interference to achieve common four-wave transverse shear interference. This sensor boasts superior detection sensitivity and anti-vibration performance, enabling real-time and high-speed dynamic interferometry without the need for vibration isolation. Real-time measurements show a frame rate exceeding 10 frames per second. Additionally, the FIS4 sensor features an ultra-high phase resolution of 512×512 (260,000 phase points), with a measurement band covering 200nm to 15μm, measurement sensitivity reaching 2nm, and measurement repeatability better than 1/1000λ (RMS). It is applicable for laser beam quality analysis, plasma flow field detection, real-time measurement of high-speed flow field distribution, optical system image quality evaluation, microscopic profile measurement, and quantitative phase imaging of biological cells.


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