The plug-and-play Biological Cell Four-wave Interferometric Sensor supports near-infrared and LED white light spectrum illumination. The imaging process does not require labeling or staining, and is capable of achieving in vivo 3D imaging at a rate of up to 24 frames per second. It can quickly be used in conjunction with any optical microscope to provide real-time measurements of the 3D phase distribution of the measured cells. It is capable of assessing cell volume and weighing. This sensor from BOJIONG is an ideal tool for label-free 3D live cell detection, biological tissue detection, germ cell detection, and micro/nano structure detection.
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Light source type |
LED, halogen lamp, and other broadband light sources |
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Wavelength range |
400nm~1100nm (for white light) |
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Target size |
7.07mm × 7.07mm |
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Spatial resolution |
13.8μ m |
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Phase output resolution |
512×512 |
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Absolute accuracy |
10nmRMS |
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Phase resolution |
≤ 2nmRMS |
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Dynamic range |
≥130μ m |
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Sampling rate |
24fps |
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Real-time processing speed |
10Hz ( At full resolution ) |
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Interface type |
GIGE |
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Dimension |
56.5mm × 43mm × 41.5mm |
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Weight |
about 120g |
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Refrigeration method |
none |
◆Label-free 3D live cell imaging
◆Single-channel light self-interference, no reference light required
◆Compact size, plug and play
◆Suitable for all optical microscope upgrades and extensions
◆Broad spectrum 400nm~1100nm band
◆Extremely strong anti-vibration performance, no need for optical vibration isolation
◆Supports LED white light and short-wave infrared light source
This BOJIONG Biological Cell Four-wave Interferometric Sensor used in labeling free 3D living cell detection, biological tissue detection, germ cell detection, micro and nano structure detection.
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Unmarked 3D live cell detection optical path detection optical path |
3D Living cell microscope - Sample measurement of roundworm eggs |
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Sample measurement of ovarian granulosa cell tumor |
Sample measurement through micro - nano structure |
BOJIONG Biological Cell Four-wave Interferometric Sensor developed by a team of professors from Zhejiang University and Nanyang Technological University of Singapore, utilizes domestic patented technology and combines diffraction and interference to achieve common four-wave transverse shear interference. This sensor boasts superior detection sensitivity and anti-vibration performance, enabling real-time and high-speed dynamic interferometry without the need for vibration isolation. Real-time measurements show a frame rate exceeding 10 frames per second. Additionally, the FIS4 sensor features an ultra-high phase resolution of 512×512 (260,000 phase points), with a measurement band covering 200nm to 15μm, measurement sensitivity reaching 2nm, and measurement repeatability better than 1/1000λ (RMS). It is applicable for laser beam quality analysis, plasma flow field detection, real-time measurement of high-speed flow field distribution, optical system image quality evaluation, microscopic profile measurement, and quantitative phase imaging of biological cells.
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No. 578 Yingkou Road, Yangpu District, Shanghai, China
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